SPIRIVA® Respimat® (tiotropium bromide)

SPIRIVA® Respimat® is indicated as an add-on maintenance bronchodilator treatment in adult patients with asthma who are currently treated with the maintenance combination of inhaled corticosteroids (≥800 μg budesonide/day or equivalent) and long-acting ß2 agonists and who experienced one or more severe exacerbations in the previous year.1

The content below contains references to information available within the Summary of Product Characteristics and other published sources.


Introducing SPIRIVA® Respimat® in asthma

SPIRIVA® Respimat® redefines what is possible by offering an additional option to help patients stay in front of asthma.


Mechanism of action

SPIRIVA® Respimat® exhibits pharmacological effects through the inhibition of M3-receptors blocking acetylcholine, which plays a significant role in the pathophysiology of asthma.2


Efficacy

The efficacy of adding SPIRIVA® Respimat® was studied, amongst others, in two replicate, randomised, placebo-controlled trials.


Safety

In the two PrimoTinA-asthma® trials adverse events and serious adverse events were well balanced between study groups and comparable to placebo.3


Dosage & administration

SPIRIVA® (tiotropium) is administered via the Respimat® Soft Mist™ Inhaler. Dosage, administration and instructions for use of the Respimat®inhaler are available here. Information about caring for and disposing of the inhaler are also provided.