SPIRIVA RESPIMAT, a Slow-moving Mist Inhaler, Is Designed for Improved Drug Delivery1-5
- Lung deposition: The mist is comprised of highly respirable, small particle-sized droplets4,5
- Inhalation effort: Unlike dry powder inhalers, the RESPIMAT inhaler operates independent of inspiratory effort to help get medication deep into patients’ lungs1,3
- Coordination: RESPIMAT may help facilitate actuation and inhalation4,5
As with all inhaled drugs, the actual amount of drug delivered to the lung may depend on patient factors, such as the coordination between the actuation of the inhaler and inspiration through the delivery system. The duration of inspiration should be at least as long as the spray duration (1.5 seconds).6View lung deposition data for RESPIMAT for asthma
RESPIMAT delivers medication efficiently and effectively to the lungs and helps reduce oropharyngeal deposition1–5
A correlation between the deposition data and clinical efficacy has not been demonstrated in large clinical trials. Active ingredients used in the studies are not commercially available in RESPIMAT. The specific physical–chemical characteristics of the drug may affect lung deposition.
*Data were collected from asthma patients. The images above are typical scintographic pictures, taken from a study patient, comparing drug deposition profiles. The percentage of dose deposition is the mean of 14 asthma study patients. Analysis of deposition in central, intermediate, and peripheral lung regions showed that deposition occurred in all 3 regions but was concentrated in the central lung region for Turbuhaler® to a greater extent than for RESPIMAT and Becloforte® (pressurized metered-dose inhaler [pMDI]). This was reflected in significantly (P<0.01) higher mean peripheral zone/central zone deposition ratios for RESPIMAT (1.34) and Becloforte (1.27) than for Turbuhaler with fast flow (0.95) or Turbuhaler with slow flow (0.82).2
The publisher for the copyrighted material is Mary Ann Liebert, Inc. publishers.
Turbuhaler is a registered trademark of AstraZeneca AB. All other trademarks are the property of their respective owners.
See the RESPIMAT Inhaler in action
You and your patients can watch this video to learn more about the RESPIMAT mist.Watch Video
See the RESPIMAT inhaler in action
With SPIRIVA RESPIMAT, remember to tell
1 DOSE = 2 PUFFS, 1 TIME EACH DAY6
In the treatment of asthma, the maximum benefits in lung function may take up to 4 to 8 weeks of dosing.
Children should use SPIRIVA RESPIMAT with the help of an adult, as instructed by their physician.
For detailed instructions, patients should refer to the Instructions for Use enclosed with their prescription.
Note: SPIRIVA RESPIMAT should not be sprayed in the eyes as this may cause blurred vision and pupil dilation.