How to use SPIRIVA HandiHaler

Use SPIRIVA HandiHaler once a day, every day to help you breathe better.

When used as directed, one daily dose of SPIRIVA HandiHaler can help keep your airways open for a full 24 hours to improve lung function as well as reduce the likelihood of COPD flare-ups (also called exacerbations). Before you use SPIRIVA HandiHaler for the first time and each time you refill your prescription, carefully read the Instructions for Use.

Using your HandiHaler

Two ways to learn: watch the how-to video or download the full Instructions for Use—including a helpful one-page overview.

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Please see Important Safety Information below.

If you have more questions about how to use SPIRIVA HandiHaler, ask your doctor for further information.

Tips for making SPIRIVA HandiHaler part of your daily routine:

When and how to clean your HandiHaler device

How do I store SPIRIVA HandiHaler?

Ask your doctor or pharmacist if you have any questions about storing your SPIRIVA capsules.

Keep SPIRIVA HandiHaler, SPIRIVA capsules, and all medicines out of the reach of children.

Get quick answers about SPIRIVA HandiHaler.


Do not use SPIRIVA HandiHaler if you are allergic to tiotropium, ipratropium, atropine or similar drugs, or any ingredient in this medicine.

SPIRIVA HandiHaler is not a rescue medicine and should not be used for treating sudden breathing problems. Your doctor may give you other medicine to use for sudden breathing problems.

SPIRIVA HandiHaler can cause allergic reactions. Symptoms can include raised red patches on your skin (hives), itching, rash and/or swelling of the lips, tongue or throat that may cause difficulty in breathing or swallowing. If you have any of these symptoms, stop taking the medicine and get immediate medical help.

Before using SPIRIVA HandiHaler, tell your doctor if you have a severe allergy to milk proteins.

SPIRIVA HandiHaler can cause your breathing to suddenly get worse (bronchospasm). If this happens, stop taking your medicine, use your rescue inhaler and call your doctor right away or go to the nearest emergency room.

Tell your doctor about all your medical conditions including kidney problems, glaucoma, enlarged prostate, problems passing urine or blockage in your bladder.

Tell your doctor all the medicines you take, including eye drops. Ask your doctor if you are taking any anticholinergic medicines because taking them together with SPIRIVA HandiHaler can increase side effects.

SPIRIVA HandiHaler can increase the pressure in your eyes (acute narrow‐angle glaucoma), which can cause the following symptoms: eye pain, blurred vision, seeing halos or colored images along with red eyes. If you have any of these symptoms, stop taking your medicine and call your doctor right away.

SPIRIVA HandiHaler can cause new or worsened urinary retention. Symptoms of blockage in your bladder and/or enlarged prostate may include difficulty passing urine and/or painful urination. If you have any of these symptoms, stop taking your medicine and call your doctor right away.

Dizziness and blurred vision may occur with SPIRIVA HandiHaler. If you experience these symptoms, use caution when engaging in activities such as driving a car or operating appliances or other machines.

The most common side effects with SPIRIVA HandiHaler include upper respiratory tract infection, dry mouth, sinus infection, sore throat, non‐specific chest pain, urinary tract infection, indigestion, runny nose, constipation, increased heart rate and blurred vision.

Do not swallow SPIRIVA capsules. The contents of the capsule should only be inhaled through your mouth using the HandiHaler device. Do not use your HandiHaler device to take other medicines.


Spiriva® HandiHaler® (tiotropium bromide inhalation powder) is a prescription medicine used once daily (a maintenance medicine) to control symptoms of chronic obstructive pulmonary disease (COPD) by relaxing your airways and keeping them open. COPD includes chronic bronchitis and emphysema.

SPIRIVA HandiHaler also reduces the likelihood of flare‐ups and worsening of COPD symptoms (COPD exacerbations).

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit or call 1-800-FDA-1088.

Please see additional Important Safety Information on the previous page. Please see full Prescribing Information, including Patient Information and Instructions for Use.


The information provided on this site is for general information and educational purposes only. You should always consult a doctor for diagnosing and treating a health or fitness problem, and before using any drug product discussed on this site.